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Avanafil or stendra is an effective medication which is used to treat erectile dysfunction or impotence in men. Avanafil is also approved by Food and Drug Administration of U.S as a treatment to erectile dysfunction. Avanafil should be only used by men according to a valid medical prescription. Erectile dysfunction is one of the most occurring sexual disorders in men. It is widely seen among older men. It is the condition when a man becomes unable to maintain an enough and good erection of the penis during a sexual activity. This happens due to insufficient flow of blood to the penis. Erection of the penis is take place by the increase of blood flow to the penis. This happens by two ways. Blood flow to the penis increases by widening of blood vessels in the penis. Also removing of blood from the penis is decreases. Thus a good erection takes place. However due to aging or other conditions like narrowing of blood vessels the erection of the penis doesn’t occur properly. This condition is known as erectile dysfunction. Avanafil helps to treat erectile dysfunction. Avanafil belongs to the class of Phosphodiesterase 5 (PDE 5) inhibitors. These PDE 5 inhibitors function by inhibiting the function of enzyme called Phosphodiesterase type- 5 and prevent it from working quickly in the body. These PDE 5 inhibitors like Avanafil, tadafil, vardenafil and sildenafil are widely used to treat erectile dysfunction in men. Avanafil is the drug which got FDA approval recently. When a man gets a sexual stimulation signals from central nervous system and the release of a chemical messenger called cyclic Guanosine Monophosphate (Cyclic GMP) begins. Cyclic GMP holds the responsibility for increasing and decreasing the size of blood vessels in the penis. When the cyclic GMP is destroyed by an enzyme called Phosphodiesterase 5 an erection is not possible. Therefore as Avanafil is a PDE 5 inhibitor, Avanafil acts on enzyme PDE 5 and inhibits its action. Therefore Avanafil enables cyclic GMP to stay for a long time. Therefore an erection of the penis is possible. Thus Avanafil is an effective drug for erectile dysfunction. However it is important to remember that Avanafil is a ‘medication’ prescribed for erectile dysfunction. Avanafil is not a tablet that is use to have ‘fun’ in a sexual activity. A generic version of Avanafil is not available yet. Avanafil can be bought as 50, 100 and 200 mg preparations. Also Avanafil should be used once per a day. Avanafil preparations are high doses than other similar drugs like Tadalafil. For most individuals with erectile dysfunction the recommended starting dose of Avanafil is 100 mg. This should be used about 30 minutes before sexual intercourse. In addition depending on the tolerability or other side effects Avanafil dose can be increased up to 200 mg or decreased to 50 mg per a day. However there may be some side effects due to intake of Avanafil. A person may experience conditions like facial flushing, headaches, nasal congestion, back pain, dizziness and some other conditions.